fibroblast growth factor receptors การใช้

• Achondroplasia is a mutation in the fibroblast growth factor receptor 3.
• Fibroblast growth factor receptor 3 has been shown to interact with FGF1 and FGF9.
• KGF is a small signaling molecule that binds to fibroblast growth factor receptor 2b ( FGFR2b ).
• FGF21 stimulates phosphorylation of fibroblast growth factor receptor substrate 2 and ERK1 / 2 in the liver.
• This syndrome is caused by a mutation in the fibroblast growth factor receptor II, located on chromosome 10.
• Cancer stem cells of rhabdomyosarcoma have been identified and fibroblast growth factor receptor 3 has been suggested as their marker.
• They interact with fibroblast growth factor receptor 1, which suggests it may be linked to the modulating of neuronal differentiation.
• Another is the lab's cloning of FRS2, which is critical for signaling by the Fibroblast growth factor receptor.
• FGFR1OP2, when fused with the fibroblast growth factor receptor 1 ( FGFR1 ), is shown to cause myeloproliferative syndrome.
• FGF3 binds to Fibroblast Growth Factor Receptor 3 ( FGFR3 ) to serve as a negative regulator of bone growth during ossification.
• The study aimed to identify the partner genes to the fibroblast growth factor receptor 1 ( FGFR1 ) involved in the syndrome.
• She discovered that similar mutations in the same gene, fibroblast growth factor receptor 2 or FGFR2, cause both Jackson Weiss syndrome and Crouzon syndrome.
• The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution.
• Three cell receptors have been described for AAV2 : heparan sulfate proteoglycan ( HSPG ), a V ? 5 integrin and fibroblast growth factor receptor 1 ( FGFR-1 ).
• The protein encoded by this gene is a member of the fibroblast growth factor receptor ( FGFR ) family, where amino acid sequence is highly conserved between members and throughout evolution.
• One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centriolin.
• These syndromes were tied to mutations in genes that produce proteins called fibroblast growth factor receptors _ molecular antennae that receive chemical signals believed to guide the development of skin, bone and neural tissues.
• In this study, bFGF was also shown to act on preosteoblasts  in the form of an increased proliferation  after binding to fibroblast growth factor receptor 1 and activating phosphoinositide 3-kinase.
• The neural cell adhesion molecule N-CAM simultaneously combines with another N-CAM and a fibroblast growth factor receptor to stimulate the tyrosine kinase activity of that receptor to induce the growth of neurites.
• Once the association between a skeletal disorder and a fibroblast growth factor receptor had been announced, scientists studying other bone diseases leapt on the possibility that their diseases might have something to do with faulty receptors.